Research and Evidence – altruvita

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Research and Evidence

Welcome to our research page for anyone who would like to view AltruVita materials about our products, research, and the evidence. Our team works hard to keep up with the latest evidence and we aim to keep you updated through the research on this page.

Targeted Health: Evidence

AltruVita’s medical and nutrition advisors have published reviews of evidence examining the relationship between diet, nutrients and botanical extracts in disease prevention.

The Role of Diet and Supplements in the Prevention and Progression of COVID-19: Current Knowledge and Open Issues

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The Potential Role of Xanthohumol in SARS-CoV-2 Treatment

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The Role of Dietary Supplements in Inflammatory Bowel Disease: A Systematic Review

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Pollution and Respiratory Disease: Can diet or supplements help? A review

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Review of the Evidence for the Use of Probiotics in Gastrointestinal Disorders

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Articles

Healthy Gut

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Curcumin

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Vitamin C

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Vitamin D

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Coenzyme Q10 & B Vitamins

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Introducing

Scientific Research

With evidence at the heart of what we do, our medical and nutrition advisors are constantly on the look out for the latest research. Here is a collection of some evidence based papers which we are frequently updating and adding to.

THE FOLLOWING LINKS COME FROM PUBMED. CLICK HERE FOR A WIDER SEARCH

Healthy Gut

Systematic review: complementary and alternative medicine in the irritable bowel syndrome.

A role for inflammation in irritable bowel syndrome?

Vitamin D Deficiency in Patients with Irritable Bowel Syndrome: Does it Exist?

Vitamin D associates with improved quality of life in participants with irritable bowel syndrome: outcomes from a pilot trial.

Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.

Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot study.

Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome.

Evaluation of Benefit and Tolerability of IQP‐CL‐101 (Xanthofen) in the Symptomatic Improvement of Irritable Bowel Syndrome: A Double‐Blinded, Randomised, Placebo‐Controlled Clinical Trial.

Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer.

Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium.

Green tea polyphenol (−) epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-γ but not by IL-4.

A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis.

Rapid cessation of acute diarrhea using a novel solution of bioactive polyphenols: a randomized trial in Nicaraguan children.

Xanthohumol

Humulus lupus extract rich in xanthohumol improves the clinical course in critically ill COVID-19 patients.

Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults.

Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial.

Xanthohumol Is a Potent Pan-Inhibitor of Coronaviruses Targeting Main Protease.

Xanthohumol and related prenylflavonoids from hops and beer: to your good health!

Bioavailability and Cardiometabolic Effects of Xanthohumol: Evidence from Animal and Human Studies

Xanthohumol exerts protective effects in liver alterations associated with aging

Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer

Novel anti-obesity effects of beer hops compound xanthohumol: role of AMPK signaling pathway

Xanthohumol ameliorates dextran sodium sulfate-induced colitis in mice by inhibiting of NF-κB signaling pathways and modulating intestinal microbiota

Xanthohumol—A Miracle Molecule with Biological Activities: A Review of Biodegradable Polymeric Carriers and Naturally Derived Compounds for Its Delivery

The Hepatic Antisteatosis Effect of Xanthohumol in High-Fat Diet-Fed Rats Entails Activation of AMPK as a Possible Protective Mechanism

Probiotics

Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease.

Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial.

The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea.

Meta-analysis of probiotics for the prevention of traveller’s diarrhoea.

The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials.

Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome.

British Dietetic Association systematic review of systematic reviews and evidence‐based practice guidelines for the use of probiotics in the management of irritable bowel syndrome in adults (2016 update).

Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: a review of clinical trials.

The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on fermented foods.

Xanthohumol—A Miracle Molecule with Biological Activities: A Review of Biodegradable Polymeric Carriers and Naturally Derived Compounds for Its Delivery

SIBO

Small intestinal bacterial overgrowth.

Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.

Herbal therapy is equivalent to rifaximin for the treatment of small intestinal bacterial overgrowth.

Curcumin

Turmeric / curcumin supplementation could improve blood pressure and endothelial function: A grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials.

Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects

Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures

Curcumin as an Antiviral Agent

Curcumin and rheumatoid arthritis: A systematic review of literature

Curcumin: A Review of Its Effects on Human Health

Curcumin effects on glycaemic indices, lipid profile, blood pressure, inflammatory markers and anthropometric measurements of non-alcoholic fatty liver disease patients: A systematic review and meta-analysis of randomized clinical trials.

A novel multi-ingredient supplement significantly improves ocular symptom severity and tear production in patients with dry eye disease: results from a randomized, placebo-controlled clinical trial.

Vitamin C

Vitamin C and Immune Function

Vitamin C: should we supplement?

Vitamin C in the Treatment of COVID-19

Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination

Vitamin C function and status in chronic disease.

Vitamin D

Vitamin D and health – The missing vitamin in humans

Vitamin D supplementation

Potential Role of Vitamin D for the Management of Depression and Anxiety

Role of Vitamin D in Athletes and Their Performance: Current Concepts and New Trends

Vitamin D, infections and immunity.

Magnesium

Magnesium supplementation beneficially affects depression in adults with depressive disorder: a systematic review and meta-analysis of randomized clinical trials.

The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials.

Understanding How Minerals Contribute to Optimal Immune Function.

Zinc, Magnesium and Vitamin K Supplementation in Vitamin D Deficiency: Pathophysiological Background and Implications for Clinical Practice.

Magnesium Disorders: Core Curriculum 2024.

Coenzyme Q10 & B Vitamins

Coenzyme Q10 supplementation - In ageing and disease.

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline.

Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease.

Alzheimer’s Disease Cooperative Study. Antioxidants for Alzheimer Disease: A Randomized Clinical Trial With Cerebrospinal Fluid Biomarker Measures.

Effect of coenzyme Q10 administration on endothelial function and extracellular superoxide dismutase in patients with ischaemic heart disease: a double-blind, randomized controlled study.

Effect of CoQ10 supplement on heart failure: a meta-analysis.

Effects of coenzyme Q10 on vascular endothelial function in humans: a meta-analysis of randomized controlled trials.

Lipophilic antioxidants prevent lipopolysaccharide-induced mitochondrial dysfunction through mitochondrial biogenesis improvement.

Effects of coenzyme Q10 supplementation (300 mg/day) on antioxidation and anti-inflammation in coronary artery disease patients during statins therapy: a randomized, placebo-controlled trial.

Markers of innate immune activity in patients with type 1 and type 2 diabetes mellitus and the effect of the anti-oxidant coenzyme Q10 on inflammatory activity.

Age-related changes in the lipid compositions of rat and human tissues.

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging.

Can Coenzyme Q10 supplementation protect the ovarian reserve against oxidative damage?

Coenzyme Q (10) treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial.

Coenzyme Q10 Intake From Food and Semen Parameters in a Subfertile Population.

The Paradox of Coenzyme Q10 in Aging

Coenzyme Q10: Clinical Applications beyond Cardiovascular Diseases

Coenzyme Q10: Clinical Applications in Cardiovascular Diseases

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