Clinically Proven. Not Just Claimed.
Clinical Trial Hub
Healthy Gut (HG01) is one of the only all-natural IBS-D (IBS with diarrhea) supplements backed by a randomised, double-blind, placebo-controlled clinical trial, considered the gold standard in clinical research.
AltruVita’s supplement has been shown to significantly reduce the symptoms of diarrhea in IBS patients, one of the most common gut conditions in the UK.
Announced at the British Gastroenterology Conference, BSG Live 2026, here's exactly what the science found:
About the trial
» 78 adult participants with moderate to severe IBS-D.
» Randomised, double-blind, placebo-controlled trial.
» Participants took two capsules, twice daily for 8 weeks.
» Carried out by The Functional Gut Health Clinic - the UK’s leading gut health clinic, helping people take control of their digestive health with fast, accurate diagnosis and expert care.
Why this trial matters
Gut problems are far more common than most people realise, and far less talked about.
» 55.5% of UK adults report experiencing a persistent gut health issue.
» 16.3% experience chronic diarrhea – that is 1 in every 6 people.
» 48.4% would rather try a natural approach before turning to prescription medication.
Source: Census Worldwide*
Healthy Gut was formulated to address exactly these problems - and now we can back it up with proper clinical evidence instead of leaving it to anecdote.
It's also why our community have left countless five-star reviews: real people, getting real relief, now confirmed by clinical data.
How the trial worked
We didn't want to just say Healthy Gut works. We wanted to prove it.
» 78 adults, (meeting Rome IV criteria for moderate-to-severe IBS-D), took part in a randomised, double-blind, placebo-controlled trial with an open-label extension.
» Neither participants nor researchers knew who was taking Healthy Gut and who was taking a placebo, removing any risk of bias in the results.
» Each participant took two capsules, twice a day.
» Symptom severity was tracked throughout using the IBS Symptom Severity Score validated clinical tool gastroenterologists use to assess IBS.
» The IBS-SSS is the clinical standard for measuring how severe someone's IBS symptoms are, covering pain, bloating, bowel habits and quality of life.
» It's widely used in gastroenterology research because it gives an objective, comparable score - rather than relying on how someone simply feels on a given day.
» Scores are graded as mild, moderate or severe.
» A reduction of 50 points or more is considered the threshold for a clinically meaningful improvement, which is why the results from this trial really stand out.
The formulation behind the result
Healthy Gut's formulation combines three heavily researched ingredients, each working in a different way.
Formulated by Prof. Martyn Caplin and AltruVita's medical and nutrition team, Healthy Gut combines:
Digestive discomfort and regular bloating had become something I just accepted as part of everyday life. Since taking Healthy Gut, I've noticed a real difference. My stomach feels much more comfortable, the bloating I regularly experienced has reduced and my digestion feels noticeably better overall. It's reassuring to see a natural product backed by clinical research, and I'm delighted that my experience reflects what the science is now showing. I would happily recommend Healthy Gut to anyone looking for support with their digestive health.
After years of dealing with bloating, digestive discomfort and inflammation, I had almost given up hope of finding something that would really help. I've tried so many products over the years, but Healthy Gut has been different. Since taking it, I've noticed a significant reduction in my symptoms and feel much more comfortable overall. It's made a genuine difference to my day-to-day wellbeing, and I'm encouraged to see clinical research supporting the benefits that I've experienced firsthand.
I've been struggling with digestive issues since my late teens, but they became particularly disruptive in my late twenties when I started travelling more for work. Early flights, busy schedules and stressful meetings would often leave me going to the toilet six, seven or even eight times a day. It was unpredictable and frustrating, and I found myself constantly worrying about when symptoms would strike next.
After starting AltruVita's Healthy Gut, I noticed a difference within a couple of weeks. The bloating reduced almost immediately, and I felt noticeably lighter. I was going to the toilet far less frequently, even during stressful periods, and when I did, things felt much more settled and predictable. I also noticed I had more energy throughout the day and wasn't needing afternoon naps anymore. Having that extra energy made it easier to introduce other healthy habits into my routine, including exercising more regularly.
The biggest difference is that I feel back in control. Before, it felt like my symptoms were dictating my day, whereas now I feel more confident and able to get on with life without constantly thinking about my gut. As strange as it sounds, the best way I can describe it is that I feel normal again. Normal is underrated, and after dealing with these issues for so many years, that feeling has made a huge difference. My advice to anyone struggling with ongoing gut symptoms would be to be brave enough to try something new because you never know what the outcome may be.
What did the experts say?
Kate Cook, Harley Street Nutritionist and founder of The Nutrition Network
“In my years as a nutritionist, I’ve seen firsthand how disruptive conditions like IBS and IBS-D are to a person's daily life. Finding a solution that actually works - and that clients feel comfortable taking long-term - is incredibly challenging.
“It is heartening to see such a rigorously researched, gold-standard clinical trial in the natural supplement space. Seeing AltruVita Healthy Gut achieve a clinically meaningful reduction on the IBS severity scale is a fantastic milestone. What excites me most is the potential impact this could have on real people. When you work with individuals struggling with IBS every day, you see how much even small improvements can mean to someone's confidence, comfort and freedom to enjoy life without constantly worrying about their symptoms.
“This gives me an exceptional, evidence-based tool to recommend to my clients, knowing it delivers real-world relief. It’s exactly the kind of robust data that elevates the whole digestive health conversation.”
Prof. Martyn Caplin, Gastroenterologist, Royal Free Hospital and AltruVita advisor
"Achieving a statistically significant and clinically relevant reduction in the IBS Symptom Severity Score demonstrates that the right natural compound can actively improve IBS symptoms."
Katie Murray, Specialist nutritionist at AltruVita
“Patients are constantly telling us that they want a natural solution to their gut issues. We have known for a while how effective AltruVita Healthy Gut is, and now we can clearly prove this works through clinical trial data.
“As a not-for-profit company, we invest heavily in research, which is almost unheard of in the natural health space. Our unique blend of highly absorbable Curcumin, low-caffeine Green Tea, and Vitamin D3 was shown to significantly contribute to digestive comfort and reduce the symptoms of IBS-D. We are giving IBS-D sufferers a scientifically backed, gentle and effective option that supports the health of the digestive tract.
“Seeing a clinically meaningful reduction in the IBS Symptom Severity Score of over fifty points during the trial is a true landmark moment. It proves that a targeted, natural approach can yield substantial relief. For patients who are desperate for structured, natural protocols without the side effects of long-term medication, this evidence-based supplement represents a significant, much-needed breakthrough in managing their gut health.”
Tara Whyand, Nutritionist
“Health professionals will often only recommend clinically trialled supplements, and therefore this represents a proven natural alternative to try with patients with IBS-D.”
HEALTHY GUT
Try the formula behind the results
🍃 Formulated to ease the symptoms of IBS, supporting a calmer, more comfortable gut.
🍃 Feel like yourself again with a science backed supplement trusted by our community and backed by clinical evidence.
🍃 Contains high quality CurcuWIN®, Green Tea + Vitamin D3.
No serious adverse events were reported during the trial, supporting Healthy Gut's profile as a well-tolerated, natural option for people managing IBS-D symptoms.
These findings are being presented as a flagship abstract at BSG LIVE '26, the British Society of Gastroenterology's annual conference - putting AltruVita's Healthy Gut results in front of the UK's leading gastroenterology community.
* About the Censuswide Consumer Research
Independent research company, Censuswide, interviewed a nationally representative sample of 1,000 UK adults between 21st March and 26th March 2026 (launched 1st April 2026).
*GB Article 13.1 Botanicals ‘on hold’ Health Claims
**Jäger R et al. comparative absorption of curcumin formulations. Nutr.j 2014;13(1):11.
***GB Nutrition and Health Claims Register